Now the question is, who will be getting the game?
Last time I checked, it'll be much like Fallout 3, but with graphical improvements, more storyline, more "free space" and such. I also think it's going to be made by Bethesda Softworks.
If you haven't watched it yet, just visit their site. The video will automatically pop up. Or do it the easy way and see a low quality version on Youtube.
BTW: I do believe that the person at the end of the video belongs to the Enclave. Absolutely sexy.